Research Articles

      Abstract    

        

INCIDENCE OF ROTAVIRUS IN THE NATIONAL CAPITAL REGION, INDIA: A RETROSPECTIVE STUDY BASED ON MULTICENTRIC DIAGNOSTIC LABORATORY

 

Dinesh Jain, Manmohan Singh, Sandeep Budhiraja, Bansidhar Tarai, Sukanya Ghildiyal

 

ABSTRACT: Background: Throughout India, severe watery dehydrating diarrhea is the major cause of morbidity and mortality in children. Rotavirus is the leading cause of severe diarrhea in children under five years of age. Objective: To examine the epidemiology of rotavirus disease across age and gender in the National Capital Region (NCR), India. Method: It is a retrospective observational study based on diagnostic laboratory data of multiple tertiary care hospital located in Delhi and NCR. The samples which were tested for rotavirus from April 2014 to July 2017 in tertiary healthcare centers; were included in the study. The overall sample size was 1942. Data analysis has been done by using MS Excel,and R. Monthly positive rates were calculated as the proportion of positive cases out of total laboratory test done for rotavirus in that month. Results: The study reported that the high-risk population groups like pediatric (0-5 years) and elderly (>64 years) were most affected with the rotavirus infection, 226 (52%) and 70 (16%) respectively. Season-wise trends of rotavirus disease showed the highest positivity during the post-monsoon and winters while decreasing trends towards summers and monsoons of the year for 2014 to 2017.The study also reported a significantly higher positivity rate among in patient population (22.8%) in comparison to outpatients (12.4%).  Conclusion: This study outlines how laboratory data analytics can be critical in understanding the epidemiology of rotavirus disease, its seasonal trend, for preventive strategies.

 

KEY WORDS: Rotavirus, Diarrhea, Pediatric population, Surveillance, Laboratory data

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