Peer Reviewed Open Access Research Journal
International Journal of Medical Laboratory Research (IJMLR)
"IJMLR invites articles for the Vol 8, Issue 2, August 2023. click to submit manuscript
ROLE OF ENDOSCOPIC CRUSH SMEAR CYTOLOGY IN DIAGNOSIS OF GIT LESIONS
SR Mittal, B Rani
ABSTRACT: Introduction: Neoplasm of gastrointestine (GIT) is one of the leading cause of death.Early detection of malignancy greatly improves the survival rate of the patients. Along with histological study of biopsy specimens, cytological study also provide an accurate reflection of many pathological processes. The present study was conducted to evaluate and compare immediate crush smear cytodiagnosis with the histopathology diagnosis. Materials and methods: 18 cases were studied in present study. Crush smears prepared and stained with MGG &PAP stain. HPE was done in 14 cases. Results: On cytology 4/18 cases were non neoplastic. Rest 11/14 cases(79%) showed correlation between cytology and Histopathology. Conclusion: Crush smear cytology is highly sensitive, specific, cheap, easier and quick procedure for identification of GIT malignancy. It can be used as an adjunct to histopathology for diagnosis of GIT lesions.
KEY WORDS: GIT, endoscopic, crush smear, cytology, histopathology
XF, Huang GM, Lu HS et al. Surgical treatment and prognosis of gastric cancer in 2613 patients. World J. Gastroentrol. 2004;10: 3405-8.
Enzinger PC, Mayer RJ. Esophageal cancer. N Engl J Med. 2003;349:2241-52.
Young JA, Hughes HE, Lee FD. Evaluation of endoscopic brush and biopsy touch smear cytology and biopsy histology in the diagnosis of carcinoma of lower esophagus and cardia. J Clin Path.1980;33:811-4.
Sharma P, Mishra V, SinghPA, Misra SP, Gupta SC. A correlative study of histology and imprint cytology in the diagnosis of gastrointestinal tract malignancies.Indian J PatholMicrobiol. 1997;40:139-46.
Rosai J. Rosai and Akerman’ssurgical pathology, 9th ed. Philadelphia: Mosby, 2004;620-87.
SA Keya, NK Saha, MJ Alam, ADHira et al. Imprint cytology in the diagnosis of upper gastrointestinal lesions.Journal of histopathology and cytology. 2018;2(1):23-9.
.DuttaG, Kar A., Mallick R, B. Susmita: Squash cytology of endoscopic biopsy specimen of gastrointestinal lesions.AJPHS. 2013;3(4):742-47.
.Kaur A., Kaur N, Bhatti A, Hura KS. The Validity of rapid intraoperative and preoperative crush smearcytology in detection of the gastrointestinal tract, gall bladder, the breast.IJAR.2017;7(7) 78-80.
.Mahadevappa A, Vijayanarashimha D Manjunath GV, Sunila R.: Application of imprint cytology in interpretation of esophageal biopsies. Journal of evolution of medical and dental sciences2013;2(24): 4350-57.
Batra M, Handa U, Mohan H, Sachdeva A. Comparison of cytohistologytechniques in diagnosis of Gastroesophageal malignancy.ActaCytologica 2008; 52:77-82.