Research Articles





Ommini Sirisha, P. Yujwal Raj*


ABSTRACT: Background: Chronic lymphocytic thyroiditis presents with a highly variable range of presentation and varying degrees of damage to the thyroid at the time of diagnosis. For most of the patients, duration of symptoms is the main criterion for consulting a medical practitioner. The present study is conducted in the rural area of Moinabad which has a high incidence of chronic lymphocytic thyroiditis and the clinical parameters, cytology grading are compared with the biochemical parameters (considered as gold standard in assessing the degree of thyroid damage) and their efficacy in predicting the degree of thyroid damage was assessed. The role of cytology grading and duration of symptoms in substituting the thyroid function tests as a method of assessment was thus being evaluated. Materials& methods: 63 cases were included in the study, conducted between January 2017 to June 2017. Clinical details, cytology findings & biochemical parameters were obtained and compared with each other using Chi-square test. Results: On comparison and statistical evaluation, cytology grading proved to be more sensitive and more predictive of damage to the thyroid gland. Conclusion: Patients can be educated that duration of symptoms can be misleading in case of Chronic Lymphocytic Thyroiditis and can be advised to consult a medical practitioner with the onset of symptoms so that damage to the thyroid gland can be prevented.


KEYWORDS: Thyroid, assessment, severity, biochemical parameters, cytology


  1. Karki S, Shrestha AFine needle aspiration cytology of thyroid and its correlation with serological findings. Department of Pathology, Tribhuvan University Teaching Hospital, Maharjagunj, Nepal. Journal of Pathology of Nepal (2017) Vol. 7, 1054 Journal of Pathology of Nepal.

  2. Gunvanti B. Rathod*, Priyanka Rai, Shwetabh Rai. A prospective study of ultrasonographic and FNAC correlation of thyroid pathology. International Archives of Integrated Medicine, Vol. 2, Issue 11, November, 2015 2(11): 46-51.

  3. Uma P, Kartheek BVS, Himaja S, Chandra Lekha J, Kasi Babu A, Bhagya Lakshmi A.

  4. Lymphocytic thyroiditis: a correlation of cytological grades with clinical, biochemical and ultrasound findings. Int J Res Med Sci 2013;1:523-31.

  5. Alka Bhatia, ArvindRajwanshi, Radharaman J Dash, Bhagwant R Mittal and Akshay K Saxena. Lymphocytic thyroiditis – is cytological grading significant? A correlation of grades with clinical, biochemical, ultrasonographic and radionuclide parameters. Cyto Journal 2007, 4:10.

  6. Neha Singh, Surendra Kumar, Vir Singh Negi, Neelaiah Siddaraju: Cytomorphologic study of Hashimoto's thyroiditis and its serologic correlation: a study of 150 cases. Acta Cytol 2009, 53: 507-516.

  7. Kumar N, Ray C, Jain S: Aspiration cytology of Hashimoto's thyroiditis in an endemic area. Cytopathol 2002, 13:31-9.

  8. Nguyen GK, Ginsberg J, Crockford PM, Villanueva RR: Hashimoto's Thyroiditis: Cytodiagnostic accuracy and pitfalls. Diagn Cytopathol 1997, 16:531-6.

  9. NeelamSood, JitendraSinghNigam. Correlation of Fine Needle Aspiration Cytology Findings with Thyroid Function Test in Cases of Lymphocytic Thyroiditis. Journal of Thyroid Research Volume 2014, Article ID 430510, 5 pages.

  10. Anila KR, Nayak N, Jayasree K. Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters. J Cytol 2016;33:145-9.

  11. Minnu Prasannan, Suja Ajoy Kumar. Hashimito’s thyroiditis - a cytomorphological study with serological correlation. IJSAR, 2(8), 2015; 47-52.

  12. Ranjini Kudva, Manjari Kishore. Hashimoto’s Thyroiditis: A Correlation of Cytolomorphology with Clinical, Biochemical & Radiological Findings. International Journal of Science and Research. Volume 4 Issue 2, February 2015.

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