International Journal of Medical Laboratory Research (IJMLR)

ASSESSMENT OF CYTOLOGY GRADING AND CLINICAL PARAMETERS IN PREDICTING THE EXTENT OF DAMAGE TO THE THYROID GLAND IN CASES OF CHRONIC LYMPHOCYTIC THYROIDITIS: A PROSPECTIVE STUDY

 

Ommini Sirisha, P. Yujwal Raj*

 

ABSTRACT: Background: Chronic lymphocytic thyroiditis presents with a highly variable range of presentation and varying degrees of damage to the thyroid at the time of diagnosis. For most of the patients, duration of symptoms is the main criterion for consulting a medical practitioner. The present study is conducted in the rural area of Moinabad which has a high incidence of chronic lymphocytic thyroiditis and the clinical parameters, cytology grading are compared with the biochemical parameters (considered as gold standard in assessing the degree of thyroid damage) and their efficacy in predicting the degree of thyroid damage was assessed. The role of cytology grading and duration of symptoms in substituting the thyroid function tests as a method of assessment was thus being evaluated. Materials& methods: 63 cases were included in the study, conducted between January 2017 to June 2017. Clinical details, cytology findings & biochemical parameters were obtained and compared with each other using Chi-square test. Results: On comparison and statistical evaluation, cytology grading proved to be more sensitive and more predictive of damage to the thyroid gland. Conclusion: Patients can be educated that duration of symptoms can be misleading in case of Chronic Lymphocytic Thyroiditis and can be advised to consult a medical practitioner with the onset of symptoms so that damage to the thyroid gland can be prevented.

 

KEYWORDS: Thyroid, assessment, severity, biochemical parameters, cytology

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