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Research Articles






AR Simon, PL Palatty, KR Thilakchand3, T George, S Abraham, S Rao, MS Baliga



Introduction: Analgesics are the main stay in the mitigation of pain in cancer patients. However, depending on the type of analgesics, adverse events which at times can be severe are also observed. In this study an attempt has been made to understand the beneficial and adverse effects of the standard analgesics recommended for mitigating cancer pain. Materials and methods: This is a cross sectional prospective observational study with 150 cancer patients requiring analgesics and was conducted at the oncology ward of a tertiary care hospital. The prescription pattern, the mitigation of pain and the adverse events were recorded. Results: The results indicate that morphine injection was the most effective followed by morphine tablets, ultracet, tramadol and paracetamol. With regard to the adverse effects it was observed that 70.7% of the patients had one or other symptoms and that constipation (9.3%; 14/150) followed by nausea (8%; 12/150) and drowsiness (5.3%; 8/150) were the most common. Conclusion: The results of the study indicate that in spite of administering protective/ preventive drugs analgesic-induced adverse effects are common in cancer patients..

KEY WORDS: Analgesics, cancer, morphine, ultracet, tramadol, paracetamol, WHO three-step ladder, adverse events.


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