Letter to Editor
Ankita Baidya, Parul Kodan, Ayan Basu, Pramod kumar, Pankaj Jorwal
Rubella in pregnancy is associated with adverse fetal outcome. As such the diagnosis of active rubella infection in a young women carries a significant importance for deciding the conception and course of pregnancy. The usual tests that are used in the diagnosis of rubella are based upon antibody detection. These tests are required to be interpreted in the context of pregnancy very carefully. In some cases the IgGavidity testing for rubella are required to be tested.
KEY WORDS: Rubella, pregnancy, serological tests, antibody
Mirambo MM, Matovelo D, Gumodoka B, Mshana SE. Acute Rubella Virus Infection among Women with Spontaneous Abortion in Mwanza City, Tanzania. . 2017;11(3):QC25-QC27. doi:10.7860/JCDR/2017/22634.9544.
Dimech W, Grangeot-Keros L, Vauloup-Fellous C. Standardization of Assays That Detect Anti-Rubella Virus IgG Antibodies. . 2016;29(1):163-174. doi:10.1128/CMR.00045-15.
Hoffmann J, Liebert UG. Significance of avidity and immunoblot analysis for rubella IgM-positive serum samples in pregnant women. J Virol Methods. 2005 Dec;130(1-2):66-71.
Thayyil J, Kuniyil V, Moorkoth AP, Rao B, Selvam P. Prevalence of rubella-specific IgG antibodies in unimmunized young female population. . 2016;5(3):658-662. doi:10.4103/2249-4863.197311.
Seker S, Abasiyanik MF, Salih BA. Rubella immune status of pregnant and non-pregnant women in Istanbul, Turkey. Saudi Med J. 2004 May;25(5):575-9.