International Journal of Medical Laboratory Research (IJMLR)

THE VALUE OF NEUTROPHIL TO LYMPHOCYTE RATIO, PLATELET COUNT AND RED CELL DISTRIBUTION WIDTH TO PLATELET RATIO AS PROGNOSTIC MARKERS IN BURN PATIENTS

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Geet Bhuyan, Chintamani Pathak , Sunil Ranga 

 

ABSTRACT: Background: The aim of the study was to find a relationship between neutrophil to lymphocyte ratio (NLR), platelet count and red cell distribution width to platelet ratio (RPR) and mortality in burn patients and whether these parameters can be used to predict the outcome in these patients. Material and methods: The retrospective study was performed on 242 patients admitted in the department of burns and plastics between February 2019 and December 2019. The study population was further divided into two groups i.e the discharge group (group 1) and the mortality group (group2).  Demographic information in both groups such as age, gender, burn scores, neutrophil counts, lymphocyte counts, platelet counts and RDW during admission to the hospital was recorded. NLR and RPR were calculated using the patient’s complete blood count (CBC). Results: NLR was higher in the mortality group (14.44±6.95) in comparison to the discharge group (7.23±3.25). RPR values were also noticeably higher in the mortality group (0.312±0.124) when compared to the discharge group (0.067±0.029). Whereas platelet count was seen to be lower in the mortality group (92.24±74.01) as compared to the discharge group (162.84±82.52). Each of the above results were statistically significant (p=0.00). These results correlated with a higher R-BAUX score that was seen in the mortality group. Conclusion: NLR, RPR and platelet count can be effectively used as prognostic markers to monitor the progression in burn patients.

 

KEY WORDS: Neutrophil to lymphocyte ratio, platelet count, red cell distribution width to platelet ratio, burn, complete blood count.

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