International Journal of Medical Laboratory Research (IJMLR)

ALTERATIONS IN HEMATOLOGICAL, LIVER AND RENAL PARAMETER LEVELS IN PEOPLE AFFLICTED WITH LUNG CANCER

 

SK Chandran , S Rao , K Prasad , S Hegde , SB Kunhanna , AK Kudva , MS Baliga

 

ABSTRACT: Background: Lung cancer is one of the most cancers in the world. It has a bad prognosis and is associated with high cancer related mortality. The present study was carried out to ascertain the alterations in the haematological, hepatic and renal parameters in lung cancer patients who were yet to receive any treatment by comparing with healthy individuals (control cohort). Methods: This was a prospective study and was conducted in a superspeciality cancer care hospital at Mangalore, Karnataka, India. The study participants included people who were confirmed to have been afflicted with lung cancer and before start of any treatment. Data was collected after obtaining the ethics committee permission and patient’s informed consent from December 2017 to February 2018. The standard blood data required for ascertaining the general health conditions were collected from patient file and analysed. Results: During the study time period, 13 females 32 males were diagnosed with lung cancer and agreed to be part of the study.  When compared to the healthy individuals, some of the haematological, liver and kidney parameters were altered in either the males or in females (p< 0.05 to 0.0002).  Conclusion: The present study indicates that there was a marked difference in the haematological, hepatic and renal parameters in people afflicted with lung cancer.

 

KEY WORDS: Lung cancer, clinical, haematological; hepatic; renal parameters.

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