Peer Reviewed Open Access Research Journal
International Journal of Medical Laboratory Research (IJMLR)
DOI: 10.35503
Case Study
Abstract
CASE STUDY: PEDIATRIC NASAL RHINOSPORIDIOSIS: RARE BUT CRITICAL DIAGNOSIS
Richa Garg,
Assistant Professor, Rama Medical College, Hapur, Uttar Pradesh
ABSTRACT: Nasal obstruction is a significant clinical complaint during adolescence and can lead to various early and late sino-nasal complications. Rhinosporidiosis, an endemic disease of Southern India, is an important differential diagnosis for nasal obstruction. Its causal organism is Rhinosporidium seeberi, a parasitic organism previously thought to be a fungus. The condition primarily involves the mucosa of the nose, nasal septum, middle nasal turbinate, and nasal floor. Surgical excision of the lesion is the preferred treatment. This article describes three cases of pediatric nasal rhinosporidiosis in Northern India diagnosed at Rama Medical College, Hapur, Uttar Pradesh, where the incidence is relatively low, leading to potential misdiagnosis during clinical examination.
KEYWORDS: Rhinosporidiosis, Nasal, Granulomatosis, Pediatric
REFERENCE:
-
Leboulanger N. Nasal obstruction in children. European Annals of Otorhinolaryngology, Head and Neck Diseases. 2016 Jun;133(3):183–6.
-
Nwawka OK, Nadgir R, Fujita A, Sakai O. Granulomatous Disease in the Head and Neck: Developing a Differential Diagnosis. RadioGraphics. 2014 Sep;34(5):1240–56.
-
Almeida FA, Feitoza L de M, Pinho JD, Mello GCF de, Lages JS, Silva FF, et al. Rhinosporidiosis: the largest case series in Brazil. Revista Da Sociedade Brasileira De Medicina Tropical. 2016;49(4):473–6.
-
Izimukwiye AI, Mbarushimana D, Ndayisaba MC, Bigirimana V, Rugwizangoga B, Laga AC. Cluster of Nasal Rhinosporidiosis, Eastern Province, Rwanda. Emerging Infectious Diseases. 2019 Sep;25(9):1727–9.
-
Ahluwalia KB. Causative Agent of Rhinosporidiosis. Journal of Clinical Microbiology. 2001 Jan;39(1):413–5.
-
Mendoza L, Taylor JW, Ajello L. The Class Mesomycetozoea: A Heterogeneous Group of Microorganisms at the Animal-Fungal Boundary. Annual Review of Microbiology. 2002 Oct;56(1):315–44.
-
Das S, Kashyap B, Barua M, Gupta N, Saha R, Vaid L, et al. Nasal rhinosporidiosis in humans: new interpretations and a review of the literature of this enigmatic disease. Medical Mycology. 2011 Apr;49(3):311–5.
-
Branscomb R. Rhinosporidiosis Update. Laboratory Medicine. 2002 Aug 1;33(8):631–3.
-
Vélez A, Jiménez G, Hidrón A, Talero S, Agudelo CA. Rhinosporidiosis in Colombia: case series and literature review. Tropical Doctor. 2018 Jul 22;48(4):289–93.
-
Devaraja K, Sagar P, Singh CA, Kumar R. Nondisseminated rhinosporidiosis with multisite involvement in the head and neck. Ear, Nose, & Throat Journal. 2018 Sep;97(9)
-
Arseculeratne SN, Atapattu DN, Wickramaratne K. Nature and significance of the electron-dense bodies of the endospores of rhinosporidium seeberi: their reactions with MTT (3-[4,5-dimethyl-2-thiazolyl]-2,5-diphenyl-2H-tetrazolium bromide) and TMRE (tetramethyl-rhodamine ethyl ester). Medical Mycology. 2005 May;43(3):261–73.
-
Bakshi SS. Rhinosporidiosis. The Journal of Allergy and Clinical Immunology In Practice. 2017;5(6):1739.
-
Chen L, Buonocore D, Wang B, Tabaee A. Delayed recurrence of sinonasal rhinosporidiosis. American Journal of Otolaryngology.