International Journal of Medical Laboratory Research (IJMLR)

BACTERIAL PROFILING OF ANTIMICROBIAL SUSCEPTIBILITY PATTERNS IN BLOOD STREAM INFECTIONS OF SUSPECTED BACTEREMIA PATIENTS FROM KANYAKUMARI DISTRICT, TAMILNADU, INDIA

 

Renjith Chandran, Srinivasa Kannan S.R, Thanga Mariappan  K, Shabeena Merrin J

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ABSTRACT: Antimicrobial resistance pattern of Bloodstream infections in patients with suspected bacteremia from Kanyakumari District, Tamil Nadu, India was surveyed for a period of 6 months and cultured as per the methods employed by CLSI. Antibiotic sensitivity was tested using Kirby-Bauer disc diffusion method.  A total of 295 bacteremia suspected patient’s blood culture samples were processed, of which 6 bacterial pathogens isolated from 27 positive blood cultures, among which 67% were gram-positive and 33% were gram-negative.The predominant isolate was coagulation negative Staphylococcusspp. (CoNS) (37%). The other isolates were Staphylococcus aureus (30%), Escherichia coli (18%), Pseudomonas aeruginosa (7%), Klebsiella pneumoniae (4%), and Enterococcus spp. (4%). The pathogens coagulase negative Staphylococcus spp and Staphylococcus aureus were more commonly resistant to Co-trimoxazole (50 to 68%) and Penicillin G (83 to 90%). Bloodstream infections are important causes of morbidity in patients, especially among the age group of 1-20 years. Prescription of proven resistant antibiotics to suspected bacteremic patients’ needs utmost attention in the study region.

KEYWORDS: Bloodstream infection- Bacterial Pathogens - Antibiotic resistance and sensitivity

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