Research Articles

      Abstract    

        

OUTCOME OF IMPLEMENTATION OF HOSPITAL INFECTION CONTROL GUIDELINES ON THE ANTIBIOTIC RESISTANCE PATTERN IN STAPHYLOCOCCUS AUREUS ISOLATED FROM SKIN AND SOFT TISSUE INFECTIONS: A RETROSPECTIVE TWO TIME POINT STUDY

Ramakrishna Pai Jakribettu, SurluVidya Rao, Ovine Loyster D’souza, Valerian Sudeep Pinto, Brincy Loyala D’souza, Laveena AgnisTellis, Manjeshwar Shrinath Baliga

 

 

ABSTRACT: BACKGROUND: Skin and soft tissue infections (SSTIs), by Staphylococcus aureus is a commonly observed phenomena. However, when the organism is methicillin-resistant S. aureus(MRSA) the morbidity is high and the organism can also lead to death of the individual if immunocompromised. Treatment of MRSA involves use of high end drugs that are extremely expensive and accompanied by side effects. METHODS: This is a retrospective study and the medical records for the year 2010 and 2015 for S aureus in SSTIs were accessed. The two time points were selected because in the beginning of the decade Hospital Infection control was upgraded and emphasized through rigorous sensitization and implementation audits. The incidence and drug resistance pattern for various clinicallyused antibiotics against S aureus at two time points were analyzed. RESULTS:The results indicated that there was a 23.24% decrease in the incidence of MRSA and was significant (p<0.019). However there was an increase in resistance of S aureus to fluoroquinolones and macrolides (p< 0.0001).CONCLUSIONS: The safety measures adopted has immense use in reducing hospital infection and be of use to public health. This study indicates that adoption of hospital infection control measures byregular practice of the stipulated guidelines is an important way in reducing the incidence of MRSA infection.

KEY WORDS: Staphylococcus aureus;MRSA; Hospital Infection Control; Skin and soft tissue infections

 

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