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Research Articles






J Kaur, G Goyal, S Singh


ABSTRACT:Background :- Gallstone disease remains a serious health concern for human beings, affecting millions of people throughout the world. Material and method:- The cross sectional study was conducted in department of Biochemistry and Surgery in Guru Gobind Singh Medical College and Hospital, Faridkot. 100 patients of chollithiasis were enrolled for study. Physical and chemical analysis of stones was done. Result:- Out of 100 gallstone patients, 36 were male and 64 were females. The biliary calculi divided into three categories, these are cholesterol stone(33), pigment stone (25)and mixed stones(42). The qualitative and quantitative analysis of biliary calculi showing the maximum amount of cholesterol was present in cholesterol stones(452.24 ± 37.02mg/gm). The maximum amount of bilirubin was present in pigment stones (4.26 ± 0.42mg/gm).The maximum amount of calcium was present in pigment stones(19.28 ± 2.10mg/gm). Mixed type of stone is more common than the cholesterol and pigmented stones. Conclusion:- From the present study, we concluded that the mean age of the patients with gall stones was 48.19 ± 10.72  years with a male-female ratio of 1:1.7. Mixed type of stone is more common than the cholesterol and pigmented stones. The categorization of gall stones based on chemical composition is required for understanding path physiology of gall stones. These manual methods are easy and cheap to do quantitative analysis of gall stones.


KEYWORDS: gall stones, cholelithiasis


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 To cite this article: Kaur J, Goyal G, Singh S; Qualitative and quantitative analysis of biliary calculi in a tertiary care hospital. Int. J. Med. Lab. Res. 2018, 3(3): 6-10

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